Phi was born with congenital heart disease, she needed open-heart surgery to survive

Donate to congenital heart disease research to help children like Phi

Your gift will help prevent children like Phi from undergoing open-heart surgery

Every day in Australia, eight babies like Phi (pictured) are born with congenital heart disease.

Before Phi was even two years old, she faced open-heart surgery.

Our scientists have discovered a simple vitamin supplement could hold the key to preventing babies like Phi from undergoing open-heart surgery.

The research breakthrough

Professor Sally Dunwoodie and her team discovered in 2017 that a deficiency in a vital molecule called NAD could cause congenital heart disease in the womb.

Not only that, but they also discovered a potential treatment, a simple vitamin B3 supplement.

Now, they are commencing Stage One clinical studies, which involves recruiting 250 women to help establish a healthy range of NAD and the simplest method to measure it.

Once the study is complete, the team can progress to Stage Two clinical trials.

How your gift will help

Stage Two clinical trials will test what level of vitamin B3 may be needed to help women with low NAD levels and potentially prevent them from having babies born with congenital heart disease.

That's where you come in. We urgently need to raise additional funding to advance this breakthrough to Stage Two - clinical trials. This will involve at least four times the number of women and could cost up to $800,000.

Will you help translate a blockbuster breakthrough into a clinical treatment that has the potential to save thousands of babies worldwide?

Acknowledgement of Country

The Victor Chang Cardiac Research Institute acknowledges the traditional custodians of the land, the Gadigal of the Eora nation, on which we meet, work, and discover.
Our Western Australian laboratories pay their respect to the Whadjuk Noongar who remain as the spiritual and cultural custodians of their land.