Sophie was born with major heart defects. Congenital heart disease has impacted her whole life

Every child deserves a healthy heart

Donate to help prevent babies from being born with damaged hearts

Your gift will provide vital funding for clinical trials that could prevent heart defects

Every day in Australia, eight babies like Sophie (pictured) are born with a damaged heart (congenital heart disease).

Sophie has endured multiple open-heart surgeries, the first before she was even a week old. She's faced a catalogue of health problems as a result of her heart defect.

A historic breakthrough reaches an exciting new stage

In 2017 our researchers discovered that a deficiency in a vital molecule called NAD could cause a range of birth defects - including heart, kidney, spinal and cleft palates. It could also be responsible for recurrent miscarriages.

Not only that, but they also discovered a potential treatment, a simple vitamin B3 supplement.

Now, they are recruiting for a world first clinical study. The study involves 250 women to help establish a healthy range of NAD and the simplest method to measure it.

We need your help to progress NAD research to clinical trials

We need to expand our study to include even more women, but we urgently need additional funding to make this possible.

Your gift will help expand our clinical study and ultimately progress to clinical trials.

Clinical trials will test what level of vitamin B3 may be needed to help women with low NAD levels and potentially prevent them from having babies born with congenital heart disease.

Help us create a future where more children start life with healthy hearts by giving generously today.

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Acknowledgement of Country

The Victor Chang Cardiac Research Institute acknowledges the traditional custodians of the land, the Gadigal of the Eora nation, on which we meet, work, and discover.
Our Western Australian laboratories pay their respect to the Whadjuk Noongar who remain as the ongoing spiritual and cultural custodians of their land.