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About us

The Victor Chang Cardiac Research Institute is an independent, not-for-profit, medical research facility that is dedicated to finding cures for cardiovascular disease. Renowned for the quality of its breakthroughs, the Victor Chang Institute is one of the most respected heart research facilities in the world. 

Established in 1994, it has now grown to a team of more than 250 dedicated staff. From the legacy of legendary heart transplant surgeon Dr Victor Chang, the team at the Victor Chang Institute has rapidly pioneered research with a shared vision – to reduce the incidence, severity and impact of heart disease, still the leading cause of death and disability in our society. 

Our values

  • To achieve excellence in research
  • To demonstrate creativity in the pursuit of scientific discovery
  • To act with honesty, integrity and fairness at all times
  • To undertake research that has significant impact and makes a difference
  • To promote a sense of teamwork and collegiality amongst staff and collaborators

At the Victor Chang Institute we strive to ensure our staff and students enjoy a great working environment. We value and are committed to providing a working environment that embraces diversity and gender equity and promotes flexible working arrangements for staff to balance working requirements and personal needs.

Come and work with us and help us make a difference.

POST DOCTORAL SCIENTIST - BIOCHEMIST

Vascular Biology

Join an international team and forge your career in biochemistry and biological chemistry.

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The Role

We are seeking an enthusiastic Post-doctoral Scientist to join an international team and who wants to forge a career in biochemistry and biological chemistry in the Vascular Biology Division, headed by Professor Roland Stocker.

 The Project

The project involves the characterization of biochemical pathways that differentiate unstable from stable atherosclerotic lesions, with the aim to fill a currently unmet but important clinical need to identify unstable plaques in humans that can give rise to heart attacks.

The focus will be on using a mouse model of unstable/vulnerable atherosclerotic plaque (Circ Res 2013;113:252) and characterizing unstable and stable plaque using non-targeted and targeted proteomics and metabolomics. The potential clinical relevance of novel biochemical parameters identified in the mouse model as being specific for vulnerable plaques will be tested by:

  1. quantifying these parameters in blood plasma samples from well characterized patients with or without acute coronary syndrome; and
  2. developing methods to detect the novel pathways identified as potential novel imaging tool for the non-invasive detection of vulnerable plaque in vivo.

 About You

The successful candidate will hold a PhD, be highly motivated, capable of independent work as well as performing well in a team, and be willing to ‘bridge’ biochemical with biomedical research.

Good interpersonal, written and oral communication skills are required.

Hands-on experience with the following is essential:

·     Experience in analytical biochemistry including LC-MS/MS

·     Experience in proteomics and/or metabolomics, including analysis of data from non-targeted ‘omics’ approach’

·     Experience in working with biological materials, preferentially mouse and human tissue

Experience and capacity to establish novel analytical methods is desirable, as is knowledge in redox chemistry/biochemistry.

What we offer:

  • Salary packaging
  • Bonus superannuation
  • State of the art facilities
  • Collaborative team environment
  • Stimulating work setting focussed on cutting edge medical research

We strive to ensure our staff and students enjoy a great working environment. We value and are committed to providing a working environment that embraces diversity and gender equity and promotes flexible working arrangements for staff to balance working requirements and personal needs.

To apply please send your cover letter, resume and contact details of three referees to recruitment@victorchang.edu.au or click below.

Applications close on 1 June 2018.

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POST DOCTORAL SCIENTIST

Computational Genomics Laboratory

Be involved in the analysis of large next-generation sequencing datasets and the development of quantitative approaches to identify the genetic causes of cardiovascular disease.

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We are seeking an enthusiastic post-doctoral scientist to join the Computational Genomics Laboratory, led by Dr Eleni Giannoulatou. The successful candidate will be involved in the analysis of large next-generation sequencing datasets and the development of quantitative approaches to identify the genetic causes of cardiovascular diseases with a particular focus on Congenital Heart Disease. The ideal candidate will have:

·   PhD in computational biology, bioinformatics, statistical genetics, or a relevant quantitative field with a demonstrated aptitude for bioinformatics research

·   Experience with a statistical programming language (R/Bioconductor or Matlab) and a scripting language (Perl or Python)

·   Excellent computational and mathematical skills

·   Strong up-to-date background in bioinformatics and its applications to genetics and next-generation sequencing

·   Demonstrated capacity to work a team member and independently and potential to supervise students

·   Excellent interpersonal and communication skills

Please address this selection criteria in your cover letter.

Term of Position

This is a full-time appointment for two years with an annual review, and the possibility of renewal subject to funding.

Salary

Salary will be commensurate with qualifications and experience, with salary packaging and superannuation options also available.

How To Apply

Please send a cover letter addressing the selection criteria, your resume and details of three referees to recruitment@victorchang.edu.au or click on the link below.

Applications close 31 March 2018

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RESEARCH ASSISTANT

Computational Genomics Laboratory

We are seeking a Bioinformatics Analyst to join a small and dynamic to help us develop quantitative approaches to identify the genetic causes of heart disease.

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We are seeking a bioinformatics analyst to join the Computational Genomics Laboratory, led by Dr Eleni Giannoulatou. The successful candidate will be involved in the analysis of large next-generation sequencing datasets and the development of quantitative approaches to identify the genetic causes of cardiovascular diseases with a particular focus on Congenital Heart Disease. The ideal candidate will have:

·   Bachelor’s degree in bioinformatics, computer science, statistics, science, engineering or a relevant quantitative field

·   Experience with a statistical programming language (R/Bioconductor or Matlab) and a scripting language (Perl or Python)

·   Excellent computational and mathematical skills

·   Background knowledge in biology and interest in genetics

·   Demonstrated capacity to work as a team member and independently

·   Excellent interpersonal and communication skills

Please address this selection criteria in your cover letter.

Term of Position

This is a full-time appointment for one year with an annual review, and the possibility of renewal subject to funding.

Salary

Salary will be commensurate with qualifications and experience, with salary packaging and superannuation options also available.

 How to Apply

If you would like to apply for this role please send your cover letter and resume to recruitment@victorchang.edu.au or click on Apply Now.

Applications close on 30 March 2018.

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COMPUTER SCIENTIST 

Computational Cardiology Group

Opportunity for a Research Assistant or Post-doctoral Scientist to join the Computational Cardiology group at the Victor Chang Cardiac Research Institute.

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This Role

Applications are invited for a Research Assistant or Post-doctoral Scientist to join the Computational Cardiology group at the Victor Chang Cardiac Research Institute.

In this position, you will use computational models of cardiac electrophysiology to evaluate the mechanism of disease in both inherited and drug-induced arrhythmias.

You will join a dynamic team of scientists working on the molecular basis of abnormal heart rhythms using state-of-the-art electrophysiology and computational techniques.

This is a full-time appointment for up to three years with the possibility of renewal subject to funding.

Skills Required 

  • Doctoral degree or relevant experience in computational biology, biomedical engineering systems biology, biophysics or related field.
  • Experience in simulation of biological processes, and programming in Matlab and C++ are essential experience with CUDA is desirable.
  • Experience with highly parallel problems and developing in high performance computing environments is desirable.
  • Basic knowledge of pharmacology and cardiac electrophysiology useful.
  • Excellent oral and written communication an ability to work within a multi-disciplinary team. 

For more details on our teams visit our website - https://www.victorchang.edu.au/heart-research/computational-cardiology

Salary

Salary will be commensurate with qualifications and experience with salary packaging and superannuation options also available.

How To Apply

Please send a cover letter, resume and the contact details for three referees to recruitment@victorchang.edu.au or click on the link below.

Applications will remain open until a suitable candidate is found.

Apply Now Download PDF

AGILENT PHD SCHOLARSHIP

Metabolomics Research Laboratory

Work in the newly established Metabolomics facility and investigate the underlying causes of atherosclerotic plaque rupture. Scholarship valued at up to $36k per annum for three years.

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Agilent PhD Scholarship

The Agilent PhD Scholarship is partially supported by Agilent Technologies. Agilent is a leader in life sciences, diagnostics and applied chemical markets. The company provides laboratories worldwide with instruments, services, consumables, applications and expertise, enabling customers to gain the insights they seek. Agilent provides a PhD Scholarship specifically to support metabolomics-based research within the Victor Chang Institute’s newly established Innovation Centre.

The successful applicant will receive up to $36k per annum (inclusive of RTP or equivalent scholarship) for three years.

Eligibility

  • A B.Sc. (Honours, Class I or II) in a biochemistry related discipline or equivalent is essential.
  • Only full-time APA (or equivalent) University Scholarship holders, or applicants with a track record competitive for an APA (or equivalent) Scholarship, are eligible to apply.
  • This project requires solid background knowledge in analytical chemistry or biochemistry, ideally with experience in mass spectrometry.

Further Information

For further information on the Agilent PhD Scholarship please download the Information Pack.

Information Pack 

Application Process

Apply for the Agilent PhD Scholarship by completing the application form and emailing your application to HR at recruitment@victorchang.edu.au or click on Apply Now.

Application Form  Apply Now

It is the intention of the Victor Chang Institute that Scholarships will be awarded annually. However as the Scholarships are prestigious, the Victor Chang Institute reserves the right not to make an award if applicants in that year are not assessed to be of the required standard.

LABORATORY HEAD, CRYO-ELECTRON MICROSCOPY

Structural & Computational Biology Division

Seeking a talented and enthusiastic individual with cryo-electron microscopy expertise.

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The Victor Chang Cardiac Research Institute (VCCRI) is seeking to hire a talented and enthusiastic individual as a Full Faculty member (Assistant or Associate Professor level) with cryo-electron microscopy expertise to join its Structural and Computational Biology Division. Preference will be given to those working on structural problems directed at cardiovascular or related biological issues.    

The successful candidate will have a conjoint academic position at the University of New South Wales (UNSW), with dedicated access to a FEI Talos Arctica microscope equipped with a Falcon III detector that has been purchased as part of the VCCRI’s new Innovation Centre, and will be housed at UNSW. The Institute also enjoys strong interactions with the University of Wollongong that has recently developed a Molecular Horizons Facility that has Talos Arctica and Titan Krios microscopes.

It is anticipated that the successful applicant will become an active member of Structural Biology communities in both Sydney and NSW. Generous start-up funds, laboratory and office space will be provided.

 

Responsibilities

The successful applicant will be expected to develop or continue a vigorous independent research program, secure and maintain extramural research funding, form collaborative projects with other faculty within the Institute and participate in graduate and postdoctoral training.

 

Requirements

Candidates will have expertise that includes single-particle cryo-EM, relevant research and teaching experience, a record of peer-reviewed publications, and a strong interest in innovative and interdisciplinary research.

The successful candidate must possess excellent communication and interpersonal skills, with the capacity to further develop linkages. Essential is a leadership style that promotes a co-operative culture throughout the Laboratory and that allows collaboration within the Institute and wider community.

 

Appointment terms & salary

The successful candidate will be offered an attractive remuneration package commensurate with your skills experience and qualifications. This position is appointed for a period of five years, renewable.

 

How to apply

For further information about the role, please download an information pack from our website:

Download Information Pack

Interested applicants should apply to Ms Maria Voukenas, Head – Human Resources at m.voukenas@victorchang.edu.au and provide a CV, contact details of three referee’s and an outline of their current and future research plans.

 Apply Now

Closing Date

Applications will be accepted until 31 March 2018.

LEAD SCIENTIST - CELL PHENOTYPING

Innovation Centre

Excellent opportunity to develop your skills and career in our brand new facility.

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About you

Are you an accomplished scientist with a talent for hands-on experimental work and complex data analysis? Are you looking to advance your career in academic research but prefer the lab bench to the office desk? Do you have a passion for science and want to work on the most exciting and cutting-edge cardiovascular research in Australia?

About us

At the Victor Chang Cardiac Research Institute, we have established a Cardiovascular Research Innovation Centre, supported by leading research scientists throughout NSW and funded by the NSW State Government. The Centre is comprised of seven cutting-edge facilities including a cell phenotyping core. This core provides functional characterisation for a range of cells including primary cardiomyocytes, cardiomyocytes differentiated from induced pluripotent stem cells, endothelial cells, heterologous expression systems and primary tissue preparations. Our specific focus is on high throughput acquisition of data relating to electrophysiology, calcium homeostasis and mechanical properties of cells in health and disease. To achieve this, we have built the core around state-of-the-art technology including:

  •  Nanion Syncropatch automated electrophysiology
  • Vala Sciences IC-200 Kinetic Imaging Cytometer
  • Axion Maestro Apex robotic multielectrode array system
  • PE Opera Phenix High Content imaging system

 The role

As lead scientist in the cell phenotyping research facility, the successful candidate will work on a range of projects with researchers from across the spectrum of the NSW cardiovascular community. You will have primary responsibility for ensuring optimal experimental design, data acquisition and data processing. You will have a strong back ground in physiology, engineering, or other relevant disciplines, and an ability to use this expertise to develop new applications of our suite of cutting-edge technology to extend the capabilities of the core facility.

Responsibilities

Duties and responsibilities include, but are not limited to:

  • Operation of high throughput phenotyping platforms
  • Provision of analytical expertise, specifically of large scale physiological datasets
  • Methods development and validation
  • Training of staff and/or postgraduate students in analytical methods
  • Facility administration including equipment maintenance, devising SOPs, maintaining chemicals, consumables, etc.

 Please apply if you satisfy the following criteria: 

  • Tertiary qualification in a relevant discipline (eg. cell biology / physiology / bioengineering / pharmacology)
  • Significant expertise in cellular electrophysiology and calcium imaging
  • Experience with analysing large data sets
  • Demonstrated experience of methods development and validation, preferably in high throughput systems

 To apply please send you cover letter, CV and details of three referees to recruitment@victorchang.edu.au or click on Apply Now.

Download PDF Apply Now

Come and work with us and make a difference.

JUNIOR SCIENTIFIC COMPUTING & DESKTOP SUPPORT

Develop your career whilst working alongside scientists performing cutting edge cardiovascular research.

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The role

This is a unique entry level role featuring 50% scientific software development and 50% desktop support.

This is a newly created role with the potential to evolve over time. We are looking to provide a new service to our scientists, this will involve talking to them, looking at what they do and writing software to solve their problems and automate repetitive tasks such as reviewing biomedical images.

Duties and responsibilities include:

Scientific Computing:

  • Speak to scientists and translate their problems into software requirements and provide solutions
  • Create software to analyse images, video and data from a range of scientific equipment
  • Create software to automate scientific tasks

Desktop Support:

  • Providing technical support, both in person or over the phone
  • Work with Microsoft Windows 7/10, Apple OSX, Microsoft Office 2010/365, Windows Server 2008/2012, Microsoft Exchange 2010
  • Installing and configuring computer hardware, software, systems, networks, printers and scanners
  • Application & Network troubleshooting
  • Setting up accounts for new users

About you

You will be a recent graduate with a talent for helping others solve and translate their problems into software requirements. Along with this you will have a strong passion to offer creative solutions to meet other’s needs.

Above all, you will have a passion for helping others and working in an environment alongside the most exciting and cutting-edge cardiovascular researchers in Australia.

 We would like to meet you if you have:

  •  University Degree in IT or Engineering
  • Proficiency in at least one programming language, such as python, R, Java or C++
  • A technical, logical thought process
  • Problem-solving skills
  • Creativity
  • Excellent customer service skills

What we offer:

  • Salary packaging
  • State of the art facilities
  • Collaborative team environment
  • Stimulating work setting focussed on cutting edge medical research

We strive to ensure our staff and students enjoy a great working environment. We value and are committed to providing a working environment that embraces diversity and gender equity and promotes flexible working arrangements for staff to balance working requirements and personal needs.

To apply please send your cover letter, CV and details of three referees to recruitment@victorchang.edu.au or click on Apply Now.

Applications will remain open until a suitable candidate is found.

Apply Now Download PDF

Come and work with us & help make a difference.

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