Phi was born with congenital heart disease, she needed open-heart surgery to survive

You can help save a child's heart.

Donate to congenital heart disease research

Your gift will provide vital funding for clinical trials that could prevent babies from being born with heart problems

Every day in Australia, eight babies like Phi (pictured) are born with congenital heart disease.

More than half will face open-heart surgery before they celebrate their first birthday. Tragically, every week four babies will die from heart problems.

Before Phi was even two years old, she faced open-heart surgery.

Can you imagine if a simple vitamin supplement could hold the key to preventing babies like Phi from undergoing open-heart surgery? If it could prevent babies from dying?

A historic breakthrough reaches an exciting new stage

Professor Sally Dunwoodie and her team discovered in 2017 that a deficiency in a vital molecule called NAD could cause congenital heart disease in the womb.

Not only that, but they also discovered a potential treatment, a simple vitamin B3 supplement.

Now, they are taking their findings to Stage One clinical study. The study involves 250 women to help establish a healthy range of NAD and the simplest method to measure it.

Once the study is complete, the team can progress to Stage Two clinical trials.

We need your help to progress NAD research to the next clinical trial

Clinical trials are costly, and the team will need to recruit at least four times the number of women from all over Australia to progress this breakthrough.

It could cost up to $800,000.

That’s where we need your help. We urgently need to raise additional funding to advance the clinical trials.

Stage Two clinical trials will test what level of vitamin B3 may be needed to help women with low NAD levels and potentially prevent them from having babies born with congenital heart disease.

We have reached a really exciting stage in congenital heart disease research, and it’s only possible thanks to the support of people like you.

This Christmas, you can help translate a blockbuster breakthrough into a clinical treatment that has the potential to save thousands of babies worldwide.

Acknowledgement of Country

The Victor Chang Cardiac Research Institute acknowledges the traditional custodians of the land, the Gadigal of the Eora nation, on which we meet, work, and discover.
Our Western Australian laboratories pay their respect to the Whadjuk Noongar who remain as the spiritual and cultural custodians of their land.

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