SAVE THE DATE
From Cardiovascular Development to Regenerative Medicine
WHAT: The Victor Chang 17th International Symposium
WHEN: Sunday 6th to Wednesday 9th November 2016
WHERE: Garvan Auditorium, 384 Victoria Street Darlinghurst, NSW
ENQUIRIES: firstname.lastname@example.org or (02) 92958763
Proudly supported by
This year’s Victor Chang International Symposium will explore the exciting, rapidly moving and controversial field of regenerative medicine and stem cell research.
Despite clinical advances over many decades, heart failure is now in epidemic proportions. One in three will die from cardiovascular causes worldwide. The engrained dogma is that the adult mammalian heart cannot regenerate after injury, instead it forms scars causing irreversible contractile dysfunction and pathology. This is in contrast to the robust regeneration seen in fetal and neonatal mammalian hearts, and in the adult hearts of amphibians and other species.
Inspired by research into these permissive models, researchers have made exciting
discoveries over the last few years that have begun to erode the view that adult
mammalian hearts cannot regenerate after injury. Stem cells are present in adult hearts and their therapeutic potential is being explored in the clinic. Furthermore, genetic, growth factor and bioengineering approaches have shown that heart regeneration can be stimulated and lost capacity rejuvenated after aging. Cardiomyocytes can be coaxed to re-enter the cell cycle and contribute to tissue replacement.
Heart regeneration will inevitably involve a complex dialogue between the different cell types in the damaged organ, including vascular cells and immune cells that invade to clear debris and foster repair. Resolution of fibrous scar and replacement of lost tissue will occur through expansion of existing cardiomyocytes and vascular cells, and may also involve stem cell-based and paracrine support mechanisms. Inevitably, the pathways and processes active during heart development form a template for heart regeneration.
At this year’s Victor Chang International Symposium we will ask how far we have come and how far we need to travel to realise the dream of heart regeneration in humans. The meeting will detail how regeneration in permissive models helps us understand and overcome the roadblocks to heart regeneration in adult humans. It will span new discoveries in heart and vascular development and growth pathways, and explore the role that stem cell systems, immune cells and cardiomyocytes play in heart regeneration and rejuvenation.
It will consider the state-of-the-art in human cardiac stem cell clinical trials, and cover the ethics and public perceptions of stem cell research and provision of unproven
commercial therapies. Regeneration science is embedded in contemporary genetics and genome science, animal biology, bioengineering and clinical medicine, all of which will be showcased at this meeting. The Symposium will feature international leaders and opinion makers in regeneration biology, as well as the emerging leaders in this field in Australia.
Confirmed international speakers include:
Professor of Medicine, Division of Cardiology, Emory University School of Medicine,
Atlanta, Georgia, USA
Professor Husain will deliver the Princesses’ Lecture on Thyroid hormone pathways and cardiac growth.
Principle Investigator, the Richard King Mellon Foundation, Children’s Hospital of
Pittsburgh; Associate Professor and Director of Research in Cardiology, Department of
Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania, USA
Scientific Director, The Jackson Laboratory, Bar Harbor, Maine, USA; Chair in
Cardiovascular Science, Imperial College London, UK
Professor of Biomedical Engineering, Duke University, Durham, North Carolina, USA
Director, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
Director, DFG Research Centre/Cluster of Excellence, Centre for Regenerative
Therapies, Dresden University of Technology, Dresden, Germany
Associate Professor, Department of Biological Regulation, Weizmann Institute of
Science, Rehovot, Israel
Principal Investigator, Department of Biological Regulation, Weizmann Institute of
Science, Rehovot, Israel
Some of the world’s greatest heart and lung transplant specialists presented their fascinating research at the 16th International Victor Chang Symposium in Sydney. The theme was “A Change of Heart, A Breath of Fresh Air”.
PROGRAM: 2015 Victor Chang Symposium Program
Professor Peter Macdonald
Victor Chang Institute, Sydney
St Vincent’s Hospital, Sydney
Mr Stephen Large
Papworth Hospital, United Kingdom
Dr Darren Freed
University of Alberta Hospital, Canada
Dr Gopala Krishna Gokhale Alla
Yashoda Hospital, India
Professor Sandrine Lecour
University of Cape Town, South Africa
Mr Andre Simon
Harefield Hospital, UK
Professor Dirk Van Raemdonck
University Hospitals Leuven, Belgium
Professor Frank Rosenfeldt
Monash University, Melbourne
Dr Daniel Chambers
Northside Heart and Lung, Queensland
Dr Greg Snell
Dr Bronwyn Levvey
Dr David McGiffin
The Alfred Hospital, Melbourne
Dr Katrina Bramstedt
Bond University, Queensland
Dr Rob Larbalestier
Heart & Lung Transplant Institute, Perth
The 15th International Victor Chang Symposium, in conjunction with St Vincent’s Hospital, was held from Thursday 23 – Saturday 25 October, 2014.
The theme of the Symposium was “Unlocking the genetic code of heart disease”.
Venue: NAB Auditorium, L2 Garvan Building, 384 Victoria St, Darlinghurst, Sydney, NSW 2010.
The Symposium will also incorporate the 2014 Princesses’ Lecture, to be given by Leslie Leinwand (pictured left) from University of Colorado, Boulder, USA.
The Symposium program will span the gamut from basic science to clinical medicine. Sessions will focus on heart development and congenital heart disease, genetic basis of dilated cardiomyopathy, cardiac muscle function and new therapies, mechanisms of cardiac hypertrophy, cardiac regeneration and stem cells, and new heart failure therapies.
CONFIRMED International Speakers
- Leslie Leinwand (University of Colorado, Boulder, USA) – Princesses’ Lecture
- Stuart Cook (Duke-NUS Graduate Medical School, Singapore)
- Peter Hunter (Auckland Bioengineering Institute, New Zealand)
- Bernard Kuhn (Boston Children’s Hospital, MA, USA)
- Wolfgang Linke (Ruhr University Bochum, Germany)
- Fady Malik (Cytokinetics, Inc. CA, USA)
- Wolfgang Rottbauer (University of Ulm, Germany)
CONFIRMED National Speakers
- Silviu Itescu (Mesoblast, Melbourne)
- David Kaye (Baker IDI, Melbourne)
- Andre La Gerche (St. Vincent’s Hospital, Melbourne)
- Julie McMullen (Baker IDI, Melbourne)
- Thomas Preiss (Australian National University, Canberra)
CONFIRMED Local Speakers
- James Chong (Westmead Millennium Institute for Medical Research)
- Sally Dunwoodie (VCCRI)
- Richard Harvey (VCCRI)
- Chris Hayward (St. Vincent’s Hospital)
- Andrew Jabbour (St. Vincent’s Hospital)
- Peter Macdonald (VCCRI)
- Chris Semsarian (University of Sydney)
- David Winlaw (Children’s Hospital, Westmead)
Please register today using this form.
Parking in Darlinghurst: Bayswater Road Secure Parking Station (24 hours); 33 Bayswater Road, 2011 Grimes – St Vincent’s Hospital Carpark; Entry Victor Street, Darlinghurst – next drive way to emergency entry.
For further information or sponsorship enquiries, please contact Ms Tanya Perre on P: +61 (2) 9295 8761 or E: email@example.com
The Public Lecture has been kindly sponsored by ClearView Wealth Limited. ClearView provides a comprehensive range of investment, superannuation, retirement and life insurance solutions as well as financial advice. It has been helping individuals, families and businesses achieve financial security and peace of mind for nearly 40 years.
ClearView is proud to be the major sponsor of the Victor Chang Public Lecture ‘Everyone Deserves a Perfect Heart’. To find out more about how ClearView can help you achieve a better financial future talk to your financial adviser today, call us on 132 976 or visit www.clearview.com.au.
The Victor Chang Institute would also like to thank:
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