FLEXcyte 96/ CardioExcyte 96 (Nanion)

The FLEXcyte 96/ CardioExcyte 96 (Nanion) is an automated, hybrid system that records both contractility and electrophysiology from cardiomyocyte networks for applications including drug screening or disease modelling. The FLEXcyte 96 allows in vitro contraction force measurements through the use of a flexible substrate.

System Specifications

• Impedance and extracellular field potentials from the same well
• FLEXcyte 96 allows in vitro contraction force measurements through the use of a flexible 10 µm thick polydimethylsiloxane membrane to mimic the elasticity of native human heart tissue.
• 96 well parallel data acquisition
• Integra Viaflow Assist provides automated multichannel pipetting for reproducible handling of cells and compounds
• Non-invasive and label-free
• Monitoring of acute and chronic drug effects
• Electrical and optical (Blue light, 470nm wavelength) pacing
• Incubation system allows for environmental control (Temperature, gas mix and humidity)

Cell Function & Screening Facility Support

• FLEXcyte 96/ CardioExcyte 96 plates (NSP-96) available for purchase from the Facility
• Experienced support personnel
• Full hands-on training and instruction for new users including:
  • cell culture requirements of the FLEXcyte 96/ CardioExcyte 96
  • setting up and running of experiments
  • data analysis using the Nanion analysis software (DataControl96)
• Fee for Service

Enquiries

Dr Jeffrey McArthur, BSc, PhD
Head, Cell Function & Screening Facility
j.mcarthur@victorchang.edu.au

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