APEX Maestro Multielectrode Array (Axion)

The APEX Maestro Multielectrode Array (Axion) is a robotic multi-electrode array platform with the capacity for automation of cell seeding, maintenance, and recording of extracellular field potentials. The APEX Maestro MEA allows for high throughput measurements or neuronal and cardiac activity from 2d or 3d cultured cells.

System Specifications

• 768 electrode amplifier
• Measures cellular activity label-free and in real-time
• Measurement of multicellular electrical properties and conduction velocities
• 24 to 96 well format
• Integrated 40 plate Liconic tissue culture incubator
• Fully enclosed in a Hamilton (Nimbus) Liquid handling robot allowing for reproducible coating/seeding/preparation/maintenance of MEA plates
• Environmental control (Temperature, CO2)
• Automated data acquisition & analysis
• Non-invasive, long term assays

Cell Function & Screening Facility Support

• Axion MEA plates available for purchase from Facility
• CytoView plates – transparent well bottom allows for culture visualization and MEA recordings
• E-STIM+ Classic MEA plates – incorporates a large simulation electrode for electrical pacing of cells during MEA recordings
• Experienced support personnel
• Full hands-on training and instruction for new users including:
• cell culture requirements of the APEX Maestro MEA
• setting up and running of experiments
• data analysis using the Axion analysis software
• Fee for Service

Enquiries

Dr Jeffrey McArthur, BSc, PhD
Head, Cell Function & Screening Facility
j.mcarthur@victorchang.edu.au

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