SyncroPatch 384PE (Nanion)

High-throughput giga-seal patch clamp platform capable of simultaneous recording from 384 cells for drug screening or functional characterisation. The SyncroPatch 384PE allows cost-effective and reproducible screening of individual compounds or compound libraries against a single or multiple targets.

System Specifications

• Giga-seal recordings
• 384 individual cells recorded simultaneously
• Integrated Biomek FX-384-pipettor arm and gripper with advanced microfluidics
• External and internal solution exchange while recording
• Temperature control
• Fast pipette dispense speed to study ligand-gated or fast desensitizing ion channels
• Single- or Multi-hole plates available (to increase signal to noise)
• Voltage- and current-clamp options available
• Able to record from many cell types:
  • Stable cell lines (HEK, CHO and others) expressing your target ion channel
  • iPS cells including cardiomyocytes (or other differentiated cells types)
  • primary cell lines
  • and others...

Cell Function & Screening Facility Support

• SyncroPatch Plates (NPC-384) available for purchase from Facility
• Experienced support personnel
• Full hands-on training and instruction for new users including:
  • cell culture requirements of the SyncroPatch
  • setting up and running of experiments
  • data analysis using the Nanion analysis software (DataControl384)
• Fee for Service

Enquiries

Dr Jeffrey McArthur, BSc, PhD
Head, Cell Function & Screening Facility
j.mcarthur@victorchang.edu.au

Discover more from the Cell Function & Screening Facility
Visit other Innovation Centre Facilities