SyncroPatch 384PE (Nanion)

SyncroPatch 384PE (Nanion)

High-throughput giga-seal patch clamp platform capable of simultaneous recording from 384 cells for drug screening or functional characterisation. The SyncroPatch 384PE allows cost-effective and reproducible screening of individual compounds or compound libraries against a single or multiple targets.

System Specifications

  • Giga-seal recordings
  • 384 individual cells recorded simultaneously
  • Integrated Biomek FX-384-pipettor arm and gripper with advanced microfluidics
  • External and internal solution exchange while recording
  • Temperature control
  • Fast pipette dispense speed to study ligand-gated or fast desensitizing ion channels
  • Single- or Multi-hole plates available (to increase signal to noise)
  • Voltage- and current-clamp options available
  • Able to record from many cell types:
    • Stable cell lines (HEK, CHO and others) expressing your target ion channel
    • iPS cells including cardiomyocytes (or other differentiated cells types)
    • primary cell lines
    • and others...

Cell Function & Screening Facility Support

  • SyncroPatch Plates (NPC-384) available for purchase from Facility
  • Experienced support personnel
  • Full hands-on training and instruction for new users including:
    • cell culture requirements of the SyncroPatch
    • setting up and running of experiments
    • data analysis using the Nanion analysis software (DataControl384)
  • Fee for Service

Enquiries

Dr Jeffrey McArthur, BSc, PhD
Head, Cell Function & Screening Facility
j.mcarthur@victorchang.edu.au


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Acknowledgement of Country

The Victor Chang Cardiac Research Institute acknowledges the traditional custodians of the land, the Gadigal of the Eora nation, on which we meet, work, and discover.
Our Western Australian laboratories pay their respect to the Whadjuk Noongar who remain as the spiritual and cultural custodians of their land.

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